Article
eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2012
Kusinski Laura C, Stanley Joanna L, Dilworth Mark R, Hirt Cassandra J, Andersson Irene J, Renshall Lewis J, Baker Bernadette C, Baker Philip N, Sibley Colin P, Wareing Mark, Glazier Jocelyn D
Abstract excerpt
Fetal growth restriction (FGR) is the inability of a fetus to reach its genetically predetermined growth potential. In the absence of a genetic anomaly or maternal undernutrition, FGR is attributable to "placental insufficiency": inappropriate maternal/fetal blood flow, reduced nutrient transport or morphological abnormalities of the placenta (e.g., altered barrier thickness). It is not known whether these...
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