Article

PHENOTYPIC CHARACTERIZATION OF TWO NOVEL CELL LINE MODELS OF CASTRATION RESISTANT PROSTATE CANCER

2021-07-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Resistance to androgen deprivation therapies is a major driver of mortality in advanced prostate cancer. Therefore, there is a need to develop new pre-clinical models that allow the investigation of resistance mechanisms and the assessment of drugs for the treatment of castration resistant prostate cancer. <h4>METHODS</h4> We generated two novel cell line models (LAPC4-CR a...

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Literature Corpus work: 708c1af1-0591-588f-a875-8acae0508d2a
DOI: 10.1101/2021.07.04.450352

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