Article

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

2020-07-03

Abstract excerpt

NCOR2 is frequently and significantly mutated in late stage androgen deprivation therapy resistant prostate cancer (ADT-RPCa). NCOR2 has been characterized as a transcriptional corepressor and has mechanistic links to DNA methylation, but its global functions and overall contributions to PCa progression remain enigmatic. In the current study, we utilize immunohistochemical staining of samples from over 700 PCa pat...

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Literature Corpus work: 5e22e25c-650e-5971-be53-90598bf1ab42
DOI: 10.1101/2020.07.02.182758

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