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Article

Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen.

BMC cancer - 25 May 2016

Takeda Keisuke, Hara Noboru, Nishiyama Tsutomu, Tasaki Masayuki, Ishizaki Fumio, Tomita Yoshihiko

Abstract excerpt

BACKGROUND: Recruitment of cofactors in the interaction of the androgen receptor (AR) and AR ligands plays a critical role in determining androgenic/antiandrogenic effects of the AR ligand on signaling, but the functions of key cofactors, including nuclear receptor coactivator (NCOA), remain poorly understood in prostate cancer cells treated with AR ligands. METHODS: We examined prostate cancer cell lines LNCaP...

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Source

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Identifiers

PMID: 27225190
DOI: 10.1186/s12885-016-2378-y
PMCID: PMC4880970

Genes

NCOA2
NCOA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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