Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An Analysis of the Effects and the Molecular Mechanism of Deep Hypothermic Low Flow on Brain Tissue in Mice.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia - 1 Jan 2016

Yang Yuzhong, Mo Xuming

Abstract excerpt

OBJECTIVES: This study examined the effects and molecular mechanisms of deep hypothermic low flow (DHLF) on brain tissue in three genotypes of 3-week-old C57BL/6 mice (N = 180). METHODS: Mice in the model condition were subjected to cerebral ischemia-reperfusion (I-R) while undergoing DHLF, then reperfused and rewarmed. Brain tissue damage was measured with 2,3,5-triphenyltetrazolium chloride (TTC) staining, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Cerebrovascular Circulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycogen Synthase Kinase 3 beta

Share to Phosphorylation

Share to Proto-Oncogene Proteins c-akt

Share to Real-Time Polymerase Chain Reaction

Share to Reperfusion Injury

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 26961480
DOI: 10.5761/atcs.oa.15-00333
PMCID: PMC4936214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An Analysis of the Effects and the Molecular Mechanism of Deep Hypothermic Low Flow on Brain Tissue in Mice.PMID 26961480Read ↗

PVT1/miR-148a-3p/MKL1 axis regulates brain damage in children with congenital heart diseaseSemantic proximity Read ↗

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in miceSemantic proximity Read ↗

[Effects of lidocaine on brain damage induced by transient global cerebral ischemia in mice of different apolipoprotein E genotypes].Semantic proximity Read ↗

Effect of 40hz Light Flicker on Cognitive Impairment and Transcriptome of Hippocampus in Right Unilateral Common Carotid Artery Occlusion MiceSemantic proximity Read ↗

Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice.Semantic proximity Read ↗

Greatly improved survival and neuroprotection in aquaporin‐4‐knockout mice following global cerebral ischemiaSemantic proximity Read ↗

Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury.Semantic proximity Read ↗

Relaxation of cardiac pericytes by GLP-1 activating K <sub>ATP</sub> channels mediates remote ischaemic preconditioning cardioprotectionSemantic proximity Read ↗

GABAergic ventrolateral preoptic projection to dorsomedial hypothalamus recapitulates post-ischemic neuroprotection by hypothermiaSemantic proximity Read ↗

Cardioprotection via brain-gut-heart signalling: GLP-1 activates KATP channels in coronary pericytesSemantic proximity Read ↗

Differences in vulnerability to permanent focal cerebral ischemia among 3 common mouse strains.Semantic proximity Read ↗

The bidirectional role of the JAK2/STAT3 signaling pathway and related mechanisms in cerebral ischemia-reperfusion injurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.