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Article

Differences in vulnerability to permanent focal cerebral ischemia among 3 common mouse strains.

Stroke - 1 Nov 2000

Majid A, He Y Y, Gidday J M, Kaplan S S, Gonzales E R, Park T S, Fenstermacher J D, Wei L, Choi D W, Hsu C Y

Abstract excerpt

BACKGROUND AND PURPOSE: Genetically engineered mice are used to study the role of single genes in cerebral ischemia, but inherent, strain-dependent differences in neuronal vulnerability may affect experimental end points. To examine this possibility, tissue injury resulting from focal ischemia and its relationship to cerebral hemodynamics were determined in 3 common mutant mouse strains. METHODS: Permanent middle...

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Identifiers

PMID: 11062298
DOI: 10.1161/01.str.31.11.2707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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