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Article

Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice.

Journal of neuroscience research - 15 Nov 2010

Fung Camille, Evans Edward, Shin Don, Shin Bo-Chul, Zhao Yuanzi, Sankar Raman, Chaudhuri Gautam, Devaskar Sherin U

Abstract excerpt

We examined the effects of 45-min hypoxia (FiO(2) 0.08; Hx) vs. normoxia (FiO(2) 0.21; Nx) on the ipsilateral (Ipsi) and contralateral (Ctrl) sides of the brain in neuronal glucose transporter isoform 3 (Glut3) heterozygous null mice (glut3(+/-)) and their wild-type littermates (WT), undergoing unilateral carotid artery ligation. Glut3(+/-) mice, under Nx, demonstrated a compensatory increase in blood-brain...

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Identifiers

PMID: 20857507
DOI: 10.1002/jnr.22487
PMCID: PMC4208918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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