Article
Massive Amplification at an Unselected Locus Accompanies Complex Chromosomal Rearrangements in Yeast.
G3 (Bethesda, Md.) - 3 May 2016
Thierry Agnès, Khanna Varun, Dujon Bernard
Abstract excerpt
Gene amplification has been observed in different organisms in response to environmental constraints, such as limited nutrients or exposure to a variety of toxic compounds, conferring them with specific phenotypic adaptations via increased expression levels. However, the presence of multiple gene copies in natural genomes has generally not been found in the absence of specific functional selection. Here, we show...
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