Article
Whole-genome sequencing of a laboratory-evolved yeast strain.
BMC genomics - 3 Feb 2010
Araya Carlos L, Payen Celia, Dunham Maitreya J, Fields Stanley
Abstract excerpt
BACKGROUND: Experimental evolution of microbial populations provides a unique opportunity to study evolutionary adaptation in response to controlled selective pressures. However, until recently it has been difficult to identify the precise genetic changes underlying adaptation at a genome-wide scale. New DNA sequencing technologies now allow the genome of parental and evolved strains of microorganisms to be...
Topics
- Algorithms
- Chromosome Breakpoints
- DNA, Fungal
- Evolution, Molecular
- Gene Dosage
- Genome, Fungal
- Genomic Library
- Point Mutation
- Polymorphism, Single Nucleotide
- Saccharomyces cerevisiae
- Sequence Analysis, DNA