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Spontaneous Changes in Ploidy Are Common in Yeast.

Current biology : CB - 19 Mar 2018

Harari Yaniv, Ram Yoav, Rappoport Nimrod, Hadany Lilach, Kupiec Martin

Abstract excerpt

Changes in ploidy are relatively rare, but play important roles in the development of cancer and the acquisition of long-term adaptations. Genome duplications occur across the tree of life, and can alter the rate of adaptive evolution. Moreover, by allowing the subsequent loss of individual chromosomes and the accumulation of mutations, changes in ploidy can promote genomic instability and/or adaptation. Although...

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PMID: 29502947
DOI: 10.1016/j.cub.2018.01.062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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