Article
Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population.
Journal of clinical pharmacy and therapeutics - 1 Jun 2016
Kadam P, Ashavaid T F, Ponde C K, Rajani R M
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVE: Statins form the backbone of lipid-lowering therapy for the prevention of cardiovascular disease. However, there is large interindividual variability in clinical response to statin treatment. Several gene variants that can be aligned to either the pharmacokinetics or pharmacodynamics of statin have been proposed as potentially important determinants of statin response. We aimed to...
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