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Article

Seventeen years of statin pharmacogenetics: a systematic review.

Pharmacogenomics - 1 Jan 2016

Leusink Maarten, Onland-Moret N Charlotte, de Bakker Paul I W, de Boer Anthonius, Maitland-van der Zee Anke H

Abstract excerpt

AIM: We evaluated the evidence of pharmacogenetic associations with statins in a systematic review. METHODS: Two separate outcomes were considered of interest: modification of low-density lipoprotein cholesterol (LDL-C) response and modification of risk for cardiovascular events. RESULTS: In candidate gene studies, 141 loci were claimed to be associated with LDL-C response. Only 5% of these associations were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26670324
DOI: 10.2217/pgs.15.158

Genes

ABCG2
APOE
LPA
SORT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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