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Article

CYP3A41B and CYP3A53 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin.

European journal of medical research - 10 Nov 2024

Maslub Mohammed G, Daud Nur Aizati Athirah, Radwan Mahasen A, Sha'aban Abubakar, Ibrahim Arafa G

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism (SNP) is a variation in the DNA sequence that results from the alteration of a single nucleotide in the genome. Atorvastatin is used to treat hypercholesterolemia. It belongs to a class of drugs called statins, which lower elevated levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C). Research findings on the associations between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39523378
DOI: 10.1186/s40001-024-02109-7
PMCID: PMC11552228

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