Article
Personalised medicine in hypercholesterolaemia: the role of pharmacogenetics in statin therapy.
Annals of medicine - 1 Dec 2020
Ahangari Najmeh, Doosti Mohammad, Ghayour Mobarhan Majid, Sahebkar Amirhossein, Ferns Gordon A, Pasdar Alireza
Abstract excerpt
Statins are the first-line choice in Lipid-lowering therapy to reduce cardiovascular risk. In a continuous attempt to optimise treatment success, there is a need for additional research on genes and related molecular pathways that can determine the efficacy and toxicity of lipid-lowering drugs. Several variations within genes associated with lipid metabolism, including those involved in uptake, distribution and...
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