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Article

Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.

DNA and cell biology - 1 Oct 2010

Poduri Aruna, Khullar Madhu, Bahl Ajay, Sehrawat B S, Sharma Yashpaul, Talwar Kewal K

Abstract excerpt

There is interindividual variation in lipid-lowering response to statins. The objective of this study was to investigate whether common variation in genes involved in lipid and statin metabolism modify the effect of statins on serum total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), and high-density lipoprotein-cholesterol concentration in coronary artery disease (CAD) patients. We studied the...

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Source

Identifiers

PMID: 20578904
DOI: 10.1089/dna.2009.1008

Genes

ABCB1
CETP
HMGCR
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.PMID 20578904Read ↗

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