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Article

Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjects.

Drug design, development and therapy - 1 Jan 2017

Woo Hye In, Kim Suk Ran, Huh Wooseong, Ko Jae-Wook, Lee Soo-Youn

Abstract excerpt

BACKGROUND: Statins are effective agents in the primary and secondary prevention of cardiovascular disease, but treatment response to statins varies among individuals. We analyzed multiple genetic polymorphisms and assessed pharmacokinetic and lipid-lowering responses after atorvastatin 80 mg treatment in healthy Korean individuals. METHODS: Atorvastatin 80 mg was given to 50 healthy Korean male volunteers. Blood...

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Identifiers

PMID: 28435225
DOI: 10.2147/DDDT.S131487
PMCID: PMC5391214

Genes

ABCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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