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Article

Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter.

Development (Cambridge, England) - 1 Mar 2016

Abdolazimi Yassan, Stojanova Zlatka, Segil Neil

Abstract excerpt

Determination of cell fate within the prosensory domain of the developing cochlear duct relies on the temporal and spatial regulation of the bHLH transcription factor Atoh1. Auditory hair cells and supporting cells arise in a wave of differentiation that patterns them into discrete rows mediated by Notch-dependent lateral inhibition. However, the mechanism responsible for selecting sensory cells from within the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transdifferentiation

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Identifiers

PMID: 26932672
DOI: 10.1242/dev.129320
PMCID: PMC4813338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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