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Article

Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea.

Scientific reports - 21 Jun 2019

Wilkerson Brent A, Chitsazan Alex D, VandenBosch Leah S, Wilken Matthew S, Reh Thomas A, Bermingham-McDonogh Olivia

Abstract excerpt

Hearing loss is often due to the absence or the degeneration of hair cells in the cochlea. Understanding the mechanisms regulating the generation of hair cells may therefore lead to better treatments for hearing disorders. To elucidate the transcriptional control mechanisms specifying the progenitor cells (i.e. prosensory cells) that generate the hair cells and support cells critical for hearing function, we...

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Share to Chromatin
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Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31227770
DOI: 10.1038/s41598-019-45515-2
PMCID: PMC6588700

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