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Article

EYA1-SIX1 complex in neurosensory cell fate induction in the mammalian inner ear.

Hearing research - 1 Mar 2013

Wong Elaine Y M, Ahmed Mohi, Xu Pin-Xian

Abstract excerpt

The phosphatase-transactivator EYA1 interacts with the homeodomain protein SIX1 to form transcriptional activation complexes, which play essential roles in regulating cell proliferation, survival and induction of sensory and neuronal differentiation programs during inner ear development. Mutation...

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Topics

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Share to Cell Lineage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hair Cells, Auditory

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Source

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Identifiers

PMID: 23104013
DOI: 10.1016/j.heares.2012.09.009
PMCID: PMC6592049

Genes

EYA1
SIX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23104013-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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