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Article

The neuropilin-like protein ESDN regulates insulin signaling and sensitivity.

American journal of physiology. Heart and circulatory physiology - 1 May 2016

Li Xuan, Jung Jae-Joon, Nie Lei, Razavian Mahmoud, Zhang Jiasheng, Samuel Varman, Sadeghi Mehran M

Abstract excerpt

Insulin effects on cell metabolism, growth, and survival are mediated by its binding to, and activation of, insulin receptor. With increasing prevalence of insulin resistance and diabetes there is considerable interest in identifying novel regulators of insulin signal transduction. The transmembrane protein endothelial and smooth muscle cell-derived neuropilin-like protein (ESDN) is a novel regulator of vascular...

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Identifiers

PMID: 26921437
DOI: 10.1152/ajpheart.00782.2015
PMCID: PMC4867389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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