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Article

Ecscr regulates insulin sensitivity and predisposition to obesity by modulating endothelial cell functions.

Nature communications - 1 Jan 2013

Akakabe Yoshiki, Koide Masahiro, Kitamura Youhei, Matsuo Kiyonari, Ueyama Tomomi, Matoba Satoaki, Yamada Hiroyuki, Miyata Keishi, Oike Yuichi, Ikeda Koji

Abstract excerpt

Insulin resistance is closely associated with obesity and is one of the earliest symptoms of type-2 diabetes. Endothelial cells are involved in the pathogenesis of insulin resistance through their role in insulin delivery and adipose tissue angiogenesis. Here we show that Ecscr (endothelial cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24022200
DOI: 10.1038/ncomms3389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24022200-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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