Article
Obesity in Children with Leptin Receptor Gene Polymorphisms.
Acta medica (Hradec Kralove) - 1 Jan 2021
Abaturov Aleksandr, Nikulina Anna
Abstract excerpt
INTRODUCTION: The study of single nucleotide polymorphisms (SNPs) of the leptin receptor gene (LEPR) based on next generation genomic sequencing (NGS) data is becoming an increasingly important aspect of diagnosis, treatment and prevention of both metabolically healthy (MHO) and metabolically unhealthy obesity (MUO) phenotypes. MATERIAL AND METHODS: 35 obese children 6-18 years old were examined by the NGS method...
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