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Article

Large copy-number variations are enriched in cases with moderate to extreme obesity.

Diabetes - 1 Oct 2010

Wang Kai, Li Wei-Dong, Glessner Joseph T, Grant Struan F A, Hakonarson Hakon, Price R Arlen

Abstract excerpt

OBJECTIVE: Obesity is an increasingly common disorder that predisposes to several medical conditions, including type 2 diabetes. We investigated whether large and rare copy-number variations (CNVs) differentiate moderate to extreme obesity from never-overweight control subjects. RESEARCH DESIGN AND METHODS: Using single nucleotide polymorphism (SNP) arrays, we performed a genome-wide CNV survey on 430 obese case...

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Source

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Identifiers

PMID: 20622171
DOI: 10.2337/db10-0192
PMCID: PMC3279563

Genes

UCP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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