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Article

Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2016

Dirican Ebubekir, Akkiprik Mustafa, Özer Ayşe

Abstract excerpt

Breast cancer (BCa) is the most common cancer and the second cause of death among women. Phosphoinositide 3-kinase (PI3K) signaling pathway has a crucial role in the cellular processes such as cell survival, growth, division, and motility. Moreover, oncogenic mutations in the PI3K pathway generally involve the activation phosphatidylinositol-4,5-bisphosphate 3-kinase-catalytic subunit alpha (PIK3CA) mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26921096
DOI: 10.1007/s13277-016-4924-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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