Article
Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women.
Technology in cancer research & treatment - 1 Jan 2000
Lian Jing, Xu En-Wei, Xi Yan-Feng, Wang Hui-Wen, Bu Peng, Wang Jin-Fen, Wang Li-Xia
Abstract excerpt
PURPOSE: Mutations of PIK3CA have recently been shown to play an important role in the pathogenesis and progression of breast neoplasms. The prevalence of PIK3CA in Chinese breast cancer patients may be underestimated. Therefore, we investigated the distribution of somatic PIK3CA mutation in Chinese breast cancer patients and explored their role in tumor phenotypes. METHODS: Mutational analysis of PIK3CA was done...
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