Article

PIK3CA mutations in breast cancer

2022-04-01

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>The phosphatidylinositide-3-kinase (PI3K) pathway regulates intracellular processes in relation to proliferation and apoptosis, which can be activated by somatic <italic>PIK3CA</italic> mutations. The aim of this work was to analyze the prevalence of <italic>PIK3CA</italic> mutations in an unselected cohort of patients with early stage breast cancer and their assoc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 67d67268-3d28-5d9e-85fb-d529af4265d0
DOI: 10.21203/rs.3.rs-1500819/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PIK3CA mutations in breast cancerDOI 10.21203/rs.3.rs-1500819/v1Read

PIK3CA-mutations in breast cancer.Semantic proximity Read

PI3K mutations in breast cancer: prognostic and therapeutic implicationsSemantic proximity Read

Survival analysis of patients with early breast cancer associated with PIK3CA mutationSemantic proximity Read

Investigation of somatic PIK3CA gene mutations in breast cancer patients.Semantic proximity Read

PIK3CAMutations in Breast Cancer Subtypes Other Than HR-Positive/HER2-NegativeSemantic proximity Read

PIK3CA somatic alterations in invasive breast cancers: different spectrum from Caucasians to Chinese detected by next generation sequencing.Semantic proximity Read

Molecular evaluation of PIK3CA gene mutation in breast cancer: determination of frequency, distribution pattern and its association with clinicopathological findings in Indian patients.Semantic proximity Read

PIK3CA Mutation is Associated with Poor Response to HER2-Targeted Therapy in Breast Cancer PatientsSemantic proximity Read

Analysis of PIK3CA Mutations with Clinicopathological Features and Prognosis in Breast cancer patients with Undergoing Neoadjuvant TherapySemantic proximity Read

Pattern of Somatic Mutations in the PIK3CA Oncogene and Their Role as a Potential Prognostic Biomarker in Breast Cancer Patients in Sri Lanka: A Pilot Study.Semantic proximity Read

PIK3CA mutations in breast cancer are associated with poor outcome.Semantic proximity Read

Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer.Semantic proximity Read