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Article

Clinicopathological and prognostic analysis of PIK3CA mutated invasive breast cancer in Chinese women.

Clinics (Sao Paulo, Brazil) - 1 Jan 2025

Chu Juhang, Huang Luyao, Wang Yaru, Qian Mingping

Abstract excerpt

OBJECTIVE: To explore the relationship between PIK3CA mutations and clinicopathological features and prognosis in breast cancer patients. METHODS: This retrospective cohort study included 283 patients with invasive breast cancer who underwent surgery from June 2017 to June 2022. PIK3CA exon 9 and 20 mutations were detected using PCR and sequencing. Patients were divided into recurrence (n = 47) and non-recurrence...

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Identifiers

PMID: 40472482
DOI: 10.1016/j.clinsp.2025.100702
PMCID: PMC12171758

Genes

PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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