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Article

Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes.

Cell reports - 1 Mar 2016

Catela Catarina, Shin Maggie M, Lee David H, Liu Jeh-Ping, Dasen Jeremy S

Abstract excerpt

The accuracy of neural circuit assembly relies on the precise spatial and temporal control of synaptic specificity determinants during development. Hox transcription factors govern key aspects of motor neuron (MN) differentiation; however, the terminal effectors of their actions are largely unknown. We show that Hox/Hox cofactor interactions coordinate MN subtype diversification and connectivity through Ret/Gfrα...

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Identifiers

PMID: 26904955
DOI: 10.1016/j.celrep.2016.01.067
PMCID: PMC4775310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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