Article
The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification.
The EMBO journal - 29 May 2013
Furlan Alessandro, Lübke Moritz, Adameyko Igor, Lallemend Francois, Ernfors Patrik
Abstract excerpt
The sympathetic nervous system relies on distinct populations of neurons that use noradrenaline or acetylcholine as neurotransmitter. We show that fating of the sympathetic lineage at early stages results in hybrid precursors from which, genetic cell-lineage tracing reveals, all types progressively emerge by principal mechanisms of maintenance, repression and induction of phenotypes. The homeobox transcription...
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