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Article

Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways.

Development (Cambridge, England) - 1 May 2017

Messéant Julien, Ezan Jérôme, Delers Perrine, Glebov Konstantin, Marchiol Carmen, Lager Franck, Renault Gilles, Tissir Fadel, Montcouquiol Mireille, Sans Nathalie, Legay Claire, Strochlic Laure

Abstract excerpt

Understanding the developmental steps that shape formation of the neuromuscular junction (NMJ) connecting motoneurons to skeletal muscle fibers is crucial. Wnt morphogens are key players in the formation of this specialized peripheral synapse, but their individual and collaborative functions and downstream pathways remain poorly understood at the NMJ. Here, we demonstrate through Wnt4 and Wnt11 gain-of-function...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28348167
DOI: 10.1242/dev.146167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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