Article
Ret signalling integrates a craniofacial muscle module during development.
Development (Cambridge, England) - 1 May 2011
Knight Robert D, Mebus Katharina, d'Angelo Arturo, Yokoya Kazutomo, Heanue Tiffany, Roehl Henry
Abstract excerpt
An appropriate organisation of muscles is crucial for their function, yet it is not known how functionally related muscles are coordinated with each other during development. In this study, we show that the development of a subset of functionally related head muscles in the zebrafish is regulated by Ret tyrosine kinase signalling. Three genes in the Ret pathway (gfra3, artemin2 and ret) are required specifically...
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