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Article

Gamma and alpha motor neurons distinguished by expression of transcription factor Err3.

Proceedings of the National Academy of Sciences of the United States of America - 11 Aug 2009

Friese Andreas, Kaltschmidt Julia A, Ladle David R, Sigrist Markus, Jessell Thomas M, Arber Silvia

Abstract excerpt

Spinal motor neurons are specified to innervate different muscle targets through combinatorial programs of transcription factor expression. Whether transcriptional programs also establish finer aspects of motor neuron subtype identity, notably the prominent functional distinction between alpha and gamma motor neurons, remains unclear. In this study, we identify DNA binding proteins with complementary expression...

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PMID: 19651609
DOI: 10.1073/pnas.0906809106
PMCID: PMC2716387

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