Article
Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb.
Neuron - 6 Apr 2006
Kramer Edgar R, Knott Laura, Su Fengyun, Dessaud Eric, Krull Catherine E, Helmbacher Françoise, Klein Rüdiger
Abstract excerpt
Establishment of limb innervation by motor neurons involves a series of hierarchical axon guidance decisions by which motor-neuron subtypes evaluate peripheral guidance cues and choose their axonal trajectory. Earlier work indicated that the pathway into the dorsal limb by lateral motor column (LMC[l]) axons requires the EphA4 receptor, which mediates repulsion elicited by ephrinAs expressed in ventral limb...
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