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Article

Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling.

Neuron - 24 Dec 2009

Bourane Steeve, Garces Alain, Venteo Stephanie, Pattyn Alexandre, Hubert Thomas, Fichard Agnes, Puech Sylvie, Boukhaddaoui Hassan, Baudet Christel, Takahashi Satoru, Valmier Jean, Carroll Patrick

Abstract excerpt

Low-threshold mechanoreceptor neurons (LTMs) of the dorsal root ganglia (DRG) are essential for touch sensation. They form highly specialized terminations in the skin and display stereotyped projections in the spinal cord. Functionally defined LTMs depend on neurotrophin signaling for their postnatal survival and functioning, but how these neurons arise during development is unknown. Here, we show that specific...

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Identifiers

PMID: 20064392
DOI: 10.1016/j.neuron.2009.12.004

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