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Article

c21orf59/kurly Controls Both Cilia Motility and Polarization.

Cell reports - 1 Mar 2016

Jaffe Kimberly M, Grimes Daniel T, Schottenfeld-Roames Jodi, Werner Michael E, Ku Tse-Shuen J, Kim Sun K, Pelliccia Jose L, Morante Nicholas F C, Mitchell Brian J, Burdine Rebecca D

Abstract excerpt

Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell polarity (PCP). Few factors that regulate both processes have been discovered. We reveal that C21orf59/Kurly (Kur), a cytoplasmic protein with some enrichment at the base of...

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Identifiers

PMID: 26904945
DOI: 10.1016/j.celrep.2016.01.069
PMCID: PMC4775428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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