Article
Defective motile cilia in Prickle2-deficient mice.
Journal of neurogenetics - 1 Jan 2000
Sowers Levi P, Yin Terry, Mahajan Vinit B, Bassuk Alexander G
Abstract excerpt
Motile cilia play diverse roles across phyla and cell types, and abnormalities in motile cilia lead to numerous disease states, including hydrocephalus. Although motile ciliary abnormalities in Prickle2 mutants have not yet been described, the planar cell polarity genes, including Prickle2, are implicated in the development and function of motile cilia. This report evaluates Prickle2-deficient mice for...
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