Article

A complex of distal appendage-associated kinases linked to human disease regulates ciliary trafficking and stability

2020-08-21

Abstract excerpt

<h4>ABSTRACT</h4> Cilia biogenesis is a complex, multi-step process involving the coordination of multiple cellular trafficking pathways. Despite the importance of ciliogenesis in mediating the cellular response to cues from the microenvironment, we have only a limited understanding of the regulation of cilium assembly. We previously identified a kinase that acts as a key regulator of ciliogenesis, TTBK2. Here, u...

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Literature Corpus work: 8b255305-418e-5bcd-98af-f2c5844c8f53
DOI: 10.1101/2020.08.21.261560

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