Article

BSImp: imputing partially observed methylation patterns for evaluating methylation heterogeneity

2021-12-09

Abstract excerpt

<h4>ABSTRACT</h4> DNA methylation is one of the most studied epigenetic modifications that has applications ranging from transcriptional regulation to aging, and can be assessed by bisulfite sequencing (BS-seq) at single base-pair resolution. The permutations of methylation statuses at bisulfite converted reads reflect the methylation patterns of individual cells. These patterns at specific genomic locations are...

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Literature Corpus work: 6040e3f4-de18-5ec7-962c-a0bfc353f353
DOI: 10.1101/2021.12.07.471020

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