Article

Improving allele-specific epigenomic signal coverage by <i>10-fold</i> using Hidden Markov Modeling and Machine Learning

2024-05-24

Abstract excerpt

Allele-specific epigenomic signals refer to differences in epigenomic patterns between the two copies, or “alleles,” of a DNA region inherited from each parent. Epigenomic patterns are defined as alterations of the DNA sequence (e.g., chemical) without modifying the underlying DNA sequence (which would be referred to as “mutations”). Mapping allele-specific epigenomic signals across a genome is crucial, as some ca...

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Literature Corpus work: 8ae1b3ad-4835-5468-babb-52d3313afc1d
DOI: 10.1101/2024.05.23.595536

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