Article
Searching Genome-Wide Multi-Locus Associations for Multiple Diseases Based on Bayesian Inference.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Guo Xuan, Zhang Jing, Cai Zhipeng, Du Ding-Zhu, Pan Yi
Abstract excerpt
Taking the advantage of high-throughput single nucleotide polymorphism (SNP) genotyping technology, large genome-wide association studies (GWASs) have been considered to hold promise for unraveling complex relationships between genotypes and phenotypes. Current multi-locus-based methods are insufficient to detect interactions with diverse genetic effects on multifarious diseases. Also, statistic tests for...
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