Article
A Bayesian multilocus association method: allowing for higher-order interaction in association studies.
Genetics - 1 Jun 2007
Albrechtsen Anders, Castella Sofie, Andersen Gitte, Hansen Torben, Pedersen Oluf, Nielsen Rasmus
Abstract excerpt
For most common diseases with heritable components, not a single or a few single-nucleotide polymorphisms (SNPs) explain most of the variance for these disorders. Instead, much of the variance may be caused by interactions (epistasis) among multiple SNPs or interactions with environmental conditions. We present a new powerful statistical model for analyzing and interpreting genomic data that influence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.