Article
A novel strategy for detecting multiple loci in Genome-Wide Association Studies of complex diseases.
International journal of bioinformatics research and applications - 1 Jan 2008
Li Jing
Abstract excerpt
Large-scale Genome-Wide Association Studies (GWAS) for complex diseases are increasingly common, due to recent advances in genotyping technology. Gene-gene interactions play an important role in the etiology of complex diseases and have to be addressed in GWAS. In this paper, an efficient strategy based on two-stage analysis is proposed. It combines a single-locus approach with a Goodness-Of-Fit (GOF) test in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
