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Article

Detecting genome-wide epistases based on the clustering of relatively frequent items.

Bioinformatics (Oxford, England) - 1 Jan 2012

Xie Minzhu, Li Jing, Jiang Tao

Abstract excerpt

MOTIVATION: In genome-wide association studies (GWAS), up to millions of single nucleotide polymorphisms (SNPs) are genotyped for thousands of individuals. However, conventional single locus-based approaches are usually unable to detect gene-gene interactions underlying complex diseases. Due to the huge search space for complicated high order interactions, many existing multi-locus approaches are slow and may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22053078
DOI: 10.1093/bioinformatics/btr603
PMCID: PMC3244765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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