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Article

Cloud computing for detecting high-order genome-wide epistatic interaction via dynamic clustering.

BMC bioinformatics - 10 Apr 2014

Guo Xuan, Meng Yu, Yu Ning, Pan Yi

Abstract excerpt

BACKGROUND: Taking the advantage of high-throughput single nucleotide polymorphism (SNP) genotyping technology, large genome-wide association studies (GWASs) have been considered to hold promise for unravelling complex relationships between genotype and phenotype. At present, traditional single-locus-based methods are insufficient to detect interactions consisting of multiple-locus, which are broadly existing in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24717145
DOI: 10.1186/1471-2105-15-102
PMCID: PMC4021249

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