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Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations.

Journal of the National Cancer Institute - 19 Mar 2003

Dite Gillian S, Jenkins Mark A, Southey Melissa C, Hocking Jane S, Giles Graham G, McCredie Margaret R E, Venter Deon J, Hopper John L

Abstract excerpt

BACKGROUND: Having a family history of breast cancer, particularly if it involves early-onset disease, is a risk factor for breast cancer, but little is known about specific causes of this association. Consequently, we studied mothers, sisters, and aunts of an age-stratified sample of 1567 unselected case patients diagnosed with breast cancer before age 60 years, recruited to a population-based,...

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PMID: 12644538
DOI: 10.1093/jnci/95.6.448

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BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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