Article
GCORE-sib: An efficient gene-gene interaction tool for genome-wide association studies based on discordant sib pairs.
BMC bioinformatics - 8 Jul 2016
Sung Pei-Yuan, Wang Yi-Ting, Hsiung Chao A, Chung Ren-Hua
Abstract excerpt
BACKGROUND: A computationally efficient tool is required for a genome-wide gene-gene interaction analysis that tests an extremely large number of single-nucleotide polymorphism (SNP) interaction pairs in genome-wide association studies (GWAS). Current tools for GWAS interaction analysis are mainly developed for unrelated case-control samples. Relatively fewer tools for interaction analysis are available for...
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