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Article

Evidence for SNP-SNP interaction identified through targeted sequencing of cleft case-parent trios.

Genetic epidemiology - 1 Apr 2017

Xiao Yanzi, Taub Margaret A, Ruczinski Ingo, Begum Ferdouse, Hetmanski Jacqueline B, Schwender Holger, Leslie Elizabeth J, Koboldt Daniel C, Murray Jeffrey C, Marazita Mary L, Beaty Terri H

Abstract excerpt

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth defect in humans, affecting 1 in 700 live births. This malformation has a complex etiology where multiple genes and several environmental factors influence risk. At least a dozen different genes have been confirmed to be associated with risk of NSCL/P in previous studies. However, all the known genetic risk factors...

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Identifiers

PMID: 28019042
DOI: 10.1002/gepi.22023
PMCID: PMC5340569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for SNP-SNP interaction identified through targeted sequencing of cleft case-parent trios.PMID 28019042Read ↗

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