Article
Altered Th17 Cytokine Expression in Helicobacter pylori Patients with TLR4 (D299G) Polymorphism.
Immunological investigations - 1 Jan 2016
Bagheri Nader, Azadegan-Dehkordi Fatemeh, Rahimian Ghorbanali, Hashemzadeh-Chaleshtori Morteza, Rafieian-Kopaei Mahmoud, Kheiri Soleyman, Gholipour Abolfazl, Shirzad Hedayatollah
Abstract excerpt
Helicobacter pylori (H. pylori) is associated with gastric ulcer and gastric adenocarcinoma. Polymorphisms in the host genes coding for Toll-like receptors (TLRs) may influence the innate and adaptive immune response to the infection, affecting the susceptibility to H. pylori or the disease outcomes. However, the details and association with different polymorphism and clinical expression of infection remain...
Topics
- Adult
- Alleles
- Amino Acid Substitution
- Biopsy
- Codon
- Cytokines
- Female
- Gene Expression Regulation
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Helicobacter Infections
- Helicobacter pylori