Article
Association of toll-like receptors 2, 4, 9 and 10 genes polymorphisms and Helicobacter pylori-related gastric diseases in Saudi patients.
Indian journal of medical microbiology - 1 Jan 2000
Eed Emad M, Hawash Yousry A, Khalifa Amany S, Alsharif Khalaf F, Alghamdi Saleh A, Almalki Abdulraheem A, Almehmadi Mazen M, Ismail Khadiga A, Taha Azza A, Saber Taisir
Abstract excerpt
Purpose: Helicobacter pylori is one of the most prevalent human pathogens worldwide. However, the outcomes of H. pylori infection are markedly variable from asymptomatic mild lesion to malignant transformation. Many factors are suggested to influence these infection outcomes, including host immunity and genetic susceptibility. Toll-like receptors (TLRs) can recognise different microbial components and play an...
Topics
- Adult
- Biopsy
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotyping Techniques
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide