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Article

The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis.

Medicine - 20 Feb 2026

Xu Zijie, Sun Xin, Dong Quanjiang, Xu Zihao, Li Zhipeng, Wang Lili

Abstract excerpt

BACKGROUND: Genetic polymorphisms in Toll-like receptor (TLR) genes have been implicated in host susceptibility to Helicobacter pylori (H pylori) infection. However, the extent to which specific single-nucleotide polymorphisms (SNPs) contribute to infection risk remains unclear. This study systematically evaluates the association between several TLR gene polymorphisms (TLR1, TLR2, TLR4, TLR5, TLR9, and TLR10) and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 41731753
DOI: 10.1097/MD.0000000000047788
PMCID: PMC12928952

Genes

TLR4
TLR10
TLR1
TLR2
TLR5
TLR9

Provenance

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